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AURKA
Oncogene
Also known as PPP1R47, BTAK, AIK, STK15, ARK1, STK6, AurA
AURKA, an intracellular kinase, is altered by mutation, amplification or overexpression in various cancer types including breast and colorectal cancers.
Show AURKA background
NCBI Gene
6790
Ensembl Gene
ENSG00000087586 (
GRCh37
/
GRCh38
)
Location
Chr20:54944445-54967393 (GRCh37)
Chr20:56369389-56392337 (GRCh38)
Ensembl Transcript
ENST00000312783 (
GRCh37
/
GRCh38
)
RefSeq
NM_003600.2 (
GRCh37
/
GRCh38
)
...
Annotated Alterations
A list of the oncogenic and mutation effects of
all OncoKB™ curated
AURKA alterations.
If you notice any mistakes or omissions, please reach out to us.
Alteration
Oncogenic
Mutation Effect
Description
Amplification
Oncogenic
Gain-of-function
F31I
Likely Oncogenic
Likely Gain-of-function
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