AURKA

Oncogene
Also known as PPP1R47, BTAK, AIK, STK15, ARK1, STK6, AurA
AURKA, an intracellular kinase, is altered by mutation, amplification or overexpression in various cancer types including breast and colorectal cancers.
Show AURKA background
NCBI Gene6790
Ensembl GeneENSG00000087586 (GRCh37/GRCh38)
Location
Chr20:54944445-54967393 (GRCh37)
Chr20:56369389-56392337 (GRCh38)
Ensembl TranscriptENST00000312783 (GRCh37/GRCh38)
RefSeqNM_003600.2 (GRCh37/GRCh38)
A list of the oncogenic and mutation effects of all OncoKB™ curated AURKA alterations.
If you notice any mistakes or omissions, please reach out to us.
Alteration
Oncogenic
Mutation Effect
Description
Amplification
Oncogenic
Gain-of-function
F31I
Likely Oncogenic
Likely Gain-of-function
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