MERTK

Oncogene
Also known as RP38, c-Eyk, Tyro12, mer
MERTK, a transmembrane tyrosine kinase, is infrequently altered in cancer.
Show MERTK background
NCBI Gene10461
Ensembl GeneENSG00000153208 (GRCh37/GRCh38)
Location
Chr2:112656056-112787138 (GRCh37)
Chr2:111898607-112029561 (GRCh38)
Ensembl TranscriptENST00000295408 (GRCh37/GRCh38)
RefSeqNM_006343.2 (GRCh37/GRCh38)
A list of the oncogenic and mutation effects of all OncoKB™ curated MERTK alterations.
If you notice any mistakes or omissions, please reach out to us.
Alteration
Oncogenic
Mutation Effect
Description
Amplification
Likely Oncogenic
Likely Gain-of-function
Y754F
Likely Neutral
Likely Loss-of-function
R758C
Likely Oncogenic
Likely Gain-of-function
R758H
Likely Oncogenic
Likely Gain-of-function
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