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Levels of Evidence
Actionable Genes
Oncology Therapies
CDx
Cancer Genes
API / License
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TMPRSS2
Also known as PRSS10
TMPRSS2, a transmembrane serine protease, is recurrently altered by chromosomal rearrangements in prostate cancer.
Show TMPRSS2 background
NCBI Gene
7113
Ensembl Gene
ENSG00000184012 (
GRCh37
/
GRCh38
)
Location
Chr21:42836478-42903043 (GRCh37)
Chr21:41464300-41531116 (GRCh38)
Ensembl Transcript
ENST00000398585 (
GRCh37
/
GRCh38
)
RefSeq
NM_001135099.1 (
GRCh37
/
GRCh38
)
...
Annotated Alterations
A list of the oncogenic and mutation effects of
all OncoKB™ curated
TMPRSS2 alterations.
If you notice any mistakes or omissions, please reach out to us.
Alteration
Oncogenic
Mutation Effect
Description
T112M
Inconclusive
Inconclusive
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